Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PARL | Q9H300 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409417 | 0.84 | PSMB8 (0.41) | PSMB8PSMB5ALDH1A1GAARAB9A | |
| SCHEMBL17767816 | 0.80 | PSMB8 (0.42) | PSMB8PSMB5MGLLKMT2AALDH1A1 | |
| SCHEMBL19658184 | 0.79 | TDP1 (0.42) | PSMB8PSMB5MGLLTDP1HRH3 | |
| SCHEMBL9752052 | 0.78 | HDAC6 (0.42) | PSMB8PSMB5 | |
| SCHEMBL436079 | 0.78 | TDP1 (0.54) | PSMB8PSMB5MGLLKMT2AALDH1A1 | |
| SCHEMBL3492697 | 0.77 | PSMB8 (0.48) | PSMB8PSMB5MGLLKMT2AALDH1A1 | |
| SCHEMBL28708767 | 0.77 | PSMB8 (0.53) | PSMB8PSMB5MGLLKMT2AALDH1A1 | |
| SCHEMBL112099 | 0.77 | FAAH (0.41) | PSMB8PSMB5KMT2AALDH1A1GAA | |
| SCHEMBL7525080 | 0.77 | APP (0.56) | ALDH1A1GAAIAPPTDP1ALOX5 | |
| SCHEMBL43576 | 0.76 | PSMB8 (0.35) | PSMB8PSMB5MGLLKMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448047-B2 | Sample processing to release nucleic acids for direct detection | APPLIED GENE TECHNOLOGIES, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6423497-B1 | LABELING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN NUCLEIC ACIDS, INCUBATE IN AMPLIFICATION MIXTURE WITH LABEL AND BINDING AGENT, EXPOSE TO LIGHT, RECOVER PRODUCT | APPLIED GENE TECHNOLOGIES, INC. | 2002-07-23 | — | — | US | disclosed |
| US-20020061537-A1 | Stabilization of nucleic acid amplification cocktails | DATTAGUPTA NANIBHUSHAN (US) | 2002-05-23 | — | — | US | disclosed |
| US-6379930-B1 | Stabilization of nucleic acid amplification cocktails | APPLIED GENE TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1192272-A2 | METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION | Applied Gene Technologies, Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2002014548-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACIDS SAMPLE PROCESSING AND AMPLIFICATION | APPLIED GENE TECHNOLOGIES, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| US-20010031473-A1 | Sample processing to release nucleic acids for direct detection | DATTAGUPTA NANIBHUSHAN (US) | 2001-10-18 | — | — | US | disclosed |
| US-6242188-B1 | Sample processing to release nucleic acids for direct detection | APPLIED GENE TECHNOLOGIES, INC. | 2001-06-05 | — | — | US | disclosed |
| US-6187566-B1 | COMPLEXES | APPLIED GENE TECHNOLOGIES, INC. | 2001-02-13 | — | — | US | disclosed |
| WO-2000053809-A2 | METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION | APPLIED GENE TECHNOLOGIES, INC. (US) | 2000-09-14 | — | — | WO | disclosed |