Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658184 | 0.92 | TDP1 (0.42) | TDP1PSMB8PSMB5FFAR1FAAH | |
| SCHEMBL1231930 | 0.91 | HDAC1 (0.50) | TDP1NPC1FAAHKMT2AMAPK1 | |
| SCHEMBL18943888 | 0.89 | NAAA (0.50) | FAAHMAPK1HPGDMAPTHDAC2 | |
| SCHEMBL17767816 | 0.89 | PSMB8 (0.42) | TDP1PSMB8PSMB5ALDH1A1FAAH | |
| SCHEMBL13163608 | 0.89 | SRD5A2 (0.48) | TDP1PSMB8PSMB5ALDH1A1FFAR1 | |
| SCHEMBL27891869 | 0.87 | PSMB8 (0.47) | TDP1PSMB8PSMB5ALDH1A1FFAR1 | |
| SCHEMBL19644254 | 0.87 | KEAP1 (0.45) | TDP1KEAP1PSMB8PSMB5ALDH1A1 | |
| SCHEMBL30363197 | 0.87 | KEAP1 (0.45) | TDP1KEAP1PSMB8PSMB5ALDH1A1 | |
| SCHEMBL300883 | 0.86 | CA12 (0.45) | TDP1PSMB8PSMB5ALDH1A1KMT2A | |
| SCHEMBL112099 | 0.86 | FAAH (0.41) | TDP1PSMB8PSMB5ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103755953-B | A kind of intelligent polycation nano-carrier, its preparation method and application thereof | SHENZHEN ADVANCED TECHNOLOGY RESEARCH INST. (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-103690961-B | A kind of intelligent amphipathic nature polyalcohol nano-micelle and its preparation method and application | SHENZHEN ADVANCED TECHNOLOGY RESEARCH INST. (CN) | 2015-09-09 | — | — | CN | claimed |
| CN-103690961-A | Intelligent amphiphilic polymer nano micelle and preparation method and application thereof | SHENZHEN INST OF ADV TECH CAS | 2014-04-02 | — | — | CN | claimed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| CN-117715914-A | Camptothecin analogs, conjugates, and methods of use | 酵活英属哥伦比亚有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |
| US-11286255-B2 | Pyridone carboxylic acid derivative or salt thereof | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-29 | — | — | US | disclosed |
| WO-2020117099-A1 | DIPEPTIDE LIGANDS OF TSPO THAT POSSESS NEUROPSYCHOTROPIC ACTIVITY | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | 2020-06-11 | — | — | WO | disclosed |
| US-20200062752-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3604305-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Wakunaga Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-9440988-B2 | Regulators of the hedgehog pathway, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2016-09-13 | — | — | US | disclosed |
| WO-2001027135-A9 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | UNIV JOHNS HOPKINS MED (US) | 2002-08-15 | — | — | WO | disclosed |
| US-20020032306-A1 | CYCLOPEPTIDE DERIVATIVES | BIOMET DEUTSCHLAND GMBH (DE) | 2002-03-14 | — | — | US | disclosed |
| WO-2001027135-A2 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2001-04-19 | — | — | WO | disclosed |
| EP-0473084-B1 | Polyethylene glycol derivatives, their modified peptides, methods for producing them and use of the modified peptides | SUMITOMO PHARMA (JP) | 1995-11-15 | — | — | EP | disclosed |
| EP-0212951-B1 | LABELLED NUCLEIC ACIDS | AMOCO CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5155216-A | Nucleic acids labeled with a chemiluminescent acridine ester | AMOCO CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| WO-1990006937-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |
| EP-0216553-A2 | Acridine ester and acridinium ester synthesis | INTEGRATED GENETICS, INC. (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0212951-A2 | Labelled nucleic acids | AMOCO CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062752-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | RAB10, HDAC10, NEK10 | TDP1 2912/4885KEAP1 2806/4885NPC1 4631/4885 |
| US-11286255-B2 | Pyridone carboxylic acid derivative or salt thereof | RARA, RAB10, RABL6 | TDP1 3043/4885KEAP1 2390/4885NPC1 4687/4885 |
| US-20020032306-A1 | CYCLOPEPTIDE DERIVATIVES | CORO1C, CYCS, CORO1A | TDP1 4455/4885KEAP1 1841/4885NPC1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.