Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526616 | 0.82 | VCAM1 (0.38) | KDM4EMEN1RECQLKMT2A | |
| Acetic Acid SCHEMBL8517054 | 0.78 | — | — | |
| SCHEMBL7516417 | 0.78 | VCAM1 (0.37) | KDM4EMEN1RECQLKMT2A | |
| SCHEMBL7523211 | 0.78 | ALOX15 (0.39) | KDM4EALOX15LMNAHPGDALDH1A1 | |
| SCHEMBL7529855 | 0.75 | PTGS2 (0.40) | KDM4EHPGDALDH1A1 | |
| SCHEMBL7519659 | 0.74 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL7522271 | 0.73 | PTGS2 (0.43) | — | |
| SCHEMBL7515293 | 0.73 | PTGS2 (0.38) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL7516065 | 0.73 | VCAM1 (0.39) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL7515913 | 0.73 | VCAM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |