Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529855 | 0.94 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL7515293 | 0.82 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL7521510 | 0.82 | ALOX15 (0.36) | — | |
| SCHEMBL7522610 | 0.79 | PTGS2 (0.37) | PTGS2 | |
| Acetic Acid SCHEMBL8517054 | 0.78 | — | — | |
| SCHEMBL7526616 | 0.78 | VCAM1 (0.38) | PTGS2 | |
| SCHEMBL7521691 | 0.77 | PTGS2 (0.36) | PTGS2 | |
| SCHEMBL7518988 | 0.74 | ALOX15 (0.38) | — | |
| SCHEMBL7516417 | 0.74 | VCAM1 (0.37) | — | |
| SCHEMBL7519086 | 0.73 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |