Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521049 | 0.92 | CYP19A1 (0.46) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7521746 | 0.91 | ALDH1A1 (0.42) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL7519941 | 0.88 | ALDH1A1 (0.44) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL3306471 | 0.86 | CYP19A1 (0.43) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL2337166 | 0.86 | CYP19A1 (0.43) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7516852 | 0.82 | ALDH1A1 (0.41) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7526818 | 0.81 | CYP19A1 (0.45) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7520904 | 0.81 | CYP19A1 (0.45) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7520858 | 0.78 | KDM4E (0.43) | CYP19A1CA1CA2CA7CA9 | |
| SCHEMBL7519643 | 0.77 | MAP3K14 (0.39) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |