SCHEMBL7521049

SCHEMBL7521049

Cc1ccc2c(c1)O[C@@](O)(c1ccccc1)[C@H](C)C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.46
MAOB P27338 4/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
MAOA P21397 1/20 0.37
CHRNB2 P17787 2/20 0.37
SLC6A2 P23975 2/20 0.37
CHRNB4 P30926 2/20 0.37
CHRNA3 P32297 2/20 0.37
CHRNA4 P43681 2/20 0.37
SLC6A3 Q01959 2/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
LMNA P02545 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTR2C P28335 1/20 0.35
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7519608 0.92 CYP19A1 (0.39) CYP19A1MAOBCHRNB2SLC6A2CHRNB4
SCHEMBL7526818 0.89 CYP19A1 (0.45) CYP19A1MAOBCRHBPCRHR2CHRNB2
SCHEMBL7520904 0.89 CYP19A1 (0.45) CYP19A1MAOBCRHBPCRHR2CHRNB2
SCHEMBL7520858 0.86 KDM4E (0.43) CYP19A1MAOBCRHBPCRHR2MAOA
SCHEMBL7523465 0.85 MAP3K14 (0.39) CYP19A1CRHBPCRHR2CHRNB2SLC6A2
SCHEMBL7519643 0.85 MAP3K14 (0.39) CYP19A1CRHBPCRHR2CHRNB2SLC6A2
SCHEMBL7521156 0.84 CYP19A1 (0.50) CYP19A1MAOBCRHBPCRHR2CA1
SCHEMBL3306471 0.83 CYP19A1 (0.43) CYP19A1MAOBCRHBPCRHR2CHRNB2
SCHEMBL2337166 0.83 CYP19A1 (0.43) CYP19A1MAOBCRHBPCRHR2CHRNB2
SCHEMBL7521746 0.83 ALDH1A1 (0.42) MAOBMAOACHRNB2SLC6A2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2742930-B1 COSMETIC EMULSION FOR EYEBROWS OR EYELASHES KAO CORP (JP) 2018-10-10 EP claimed
EP-2742930-A1 COSMETIC EMULSION FOR EYEBROWS OR EYELASHES Kao Corporation (JP) 2014-06-18 EP claimed
EP-2742930-B1 COSMETIC EMULSION FOR EYEBROWS OR EYELASHES KAO CORP (JP) 2018-10-10 EP disclosed
EP-2742930-A1 COSMETIC EMULSION FOR EYEBROWS OR EYELASHES Kao Corporation (JP) 2014-06-18 EP disclosed
EP-0743311-B1 FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME KAO CORP (JP) 2002-02-13 EP disclosed
US-5876703-A CELL DIFFERENTIATION OF HAIR MATRIX CELLS KAO CORPORATION (JP) 1999-03-02 US disclosed
US-5702691-A Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives KAO CORPORATION (JP) 1997-12-30 US disclosed
EP-0743311-A1 FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME Kao Corporation (JP) 1996-11-20 EP disclosed