Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306471 | 1.00 | CYP19A1 (0.43) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7521676 | 0.89 | MAPT (0.43) | MEN1KMT2AMAPTCYP2C19CYP3A4 | |
| SCHEMBL7520344 | 0.87 | RET (0.45) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL8484519 | 0.86 | CYP19A1 (0.47) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7519608 | 0.86 | CYP19A1 (0.39) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7516218 | 0.85 | MEN1 (0.40) | MEN1KMT2AMAPTCYP3A4ALOX15 | |
| SCHEMBL7530287 | 0.84 | OPRD1 (0.37) | CYP3A4ALOX15OPRD1MDM2 | |
| SCHEMBL7520906 | 0.84 | KDM4E (0.39) | KMT2AMAPTCYP2C19CYP3A4ALOX15 | |
| SCHEMBL7520904 | 0.83 | CYP19A1 (0.45) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7526818 | 0.83 | CYP19A1 (0.45) | CYP19A1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184052-B1 | Composition for hair | KAO GERMANY GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| EP-2258337-B1 | Composition for hair | KAO GERMANY GMBH (DE) | 2015-05-20 | — | — | EP | disclosed |
| US-8865145-B2 | Water-in-oil emulsion composition for hair | KAO GERMANY GMBH (DE) | 2014-10-21 | — | — | US | disclosed |
| EP-2358442-B1 | WATER-IN-OIL EMULSION COMPOSITION FOR HAIR | KAO GERMANY GMBH (DE) | 2013-01-09 | — | — | EP | disclosed |
| EP-2090291-B1 | Composition for hair comprising PCA and PCA ester | KPSS KAO GMBH (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2358442-A1 | WATER-IN-OIL EMULSION COMPOSITION FOR HAIR | KPSS-Kao Professional Salon Services GmbH (DE) | 2011-08-24 | — | — | EP | disclosed |
| EP-2258337-A1 | Composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-12-08 | — | — | EP | disclosed |
| US-20100178265-A1 | HAIR CONDITIONING COMPOSITION | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-07-15 | — | — | US | disclosed |
| WO-2010057615-A1 | WATER-IN-OIL EMULSION COMPOSITION FOR HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| EP-2186543-A1 | Water-in-oil emulsion composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2184052-A1 | Composition for hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-05-12 | — | — | EP | disclosed |
| EP-2090291-A1 | Composition for hair comprising PCA and PCA ester | KPSS-Kao Professional Salon Services GmbH (DE) | 2009-08-19 | — | — | EP | disclosed |
| EP-1683512-A1 | Hair conditioning composition containing flavone derivatives | KPSS-Kao Professional Salon Services GmbH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20060140887-A1 | Hair conditioning composition | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140887-A1 | Hair conditioning composition | HAAO, HAO1, HAO2 | CYP19A1 579/4885CHRNA1 3121/4885CHRNG 3180/4885 |
| US-20100178265-A1 | HAIR CONDITIONING COMPOSITION | HAAO, HAO1, HAO2 | CYP19A1 579/4885CHRNA1 3121/4885CHRNG 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.