Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338520 | 1.00 | PTGS1 (0.56) | PTGS1MAPK14PDE4BPTGS2ESR1 | |
| SCHEMBL20161084 | 0.91 | MAPK14 (0.50) | PTGS1MAPK14PTGS2HTTMAPT | |
| SCHEMBL20160837 | 0.88 | PDE4B (0.52) | PDE4BPTGS2ESR1ESR2HTT | |
| SCHEMBL13170491 | 0.88 | PDE4B (0.52) | PDE4BPTGS2ESR1ESR2HTT | |
| SCHEMBL4250744 | 0.88 | PDE4B (0.52) | PDE4BPTGS2ESR1ESR2HTT | |
| SCHEMBL13170578 | 0.88 | PDE4B (0.52) | PDE4BPTGS2ESR1ESR2HTT | |
| SCHEMBL20160807 | 0.85 | LMNA (0.52) | PDE4BPTGS2ESR1ESR2HTT | |
| SCHEMBL516326 | 0.85 | PDE4B (0.54) | PDE4BESR1ESR2HTTMEN1 | |
| Ethyne SCHEMBL28292549 | 0.80 | PDE4B (0.50) | PDE4BESR1ESR2HTTMEN1 | |
| SCHEMBL29504918 | 0.78 | ALDH1A1 (0.46) | PTGS1MAPK14PTGS2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170279-A1 | Polyphenylene oligomers and polymers | THE DOW CHEMICAL COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| US-5965679-A | BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS | THE DOW CHEMICAL COMPANY (US) | 1999-10-12 | — | — | US | claimed |
| EP-0889920-A1 | POLYPHENYLENE OLIGOMERS AND POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1998011149-A1 | POLYPHENYLENE OLIGOMERS AND POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6288188-B1 | ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS | THE DOW CHEMICAL COMPANY | 2001-09-11 | — | — | US | disclosed |