Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521247 | 0.83 | KDM4E (0.41) | ACHEALDH1A1 | |
| SCHEMBL5768074 | 0.81 | OPRM1 (0.34) | CYP2C19ALDH1A1RPS6KA2 | |
| SCHEMBL5768077 | 0.81 | OPRM1 (0.34) | CYP2C19ALDH1A1RPS6KA2 | |
| SCHEMBL5769113 | 0.81 | OPRM1 (0.34) | CYP2C19ALDH1A1RPS6KA2 | |
| SCHEMBL5769115 | 0.81 | OPRM1 (0.34) | CYP2C19ALDH1A1RPS6KA2 | |
| SCHEMBL7516886 | 0.76 | ALDH1A1 (0.38) | CYP1A2CYP2C9CYP2C19ALDH1A1RPS6KA2 | |
| SCHEMBL15485496 | 0.69 | HTR2C (0.43) | CYP1A2CYP2C9CYP2C19ACHE | |
| SCHEMBL15485406 | 0.66 | KMT2A (0.48) | ALDH1A1 | |
| SCHEMBL7426892 | 0.65 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL6957478 | 0.63 | ACHE (0.74) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | CYP1A2 2078/4885CYP2C9 1922/4885CYP2C19 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.