SCHEMBL751990

SCHEMBL751990

CCC(CC)(CP(=O)(O)O)OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630305 0.82
SCHEMBL1805268 0.81 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9644686 0.80 GRM4 (0.41) GAA
SCHEMBL144976 0.79 GAA (0.44) GAAALDH1A1LMNAHSD17B10
SCHEMBL2044764 0.78 GGPS1 (0.46)
SCHEMBL1804830 0.77 THRB (0.37) ALDH1A1HSD17B10
SCHEMBL10628363 0.74 LAP3 (0.34)
SCHEMBL2466608 0.74 GAA (0.41) GAA
SCHEMBL12776907 0.71 GAA (0.43) GAAALDH1A1LMNAHSD17B10
SCHEMBL7636622 0.71 GAA (0.43) GAAALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421225-B2 Heteroaromatic amide derivative and medicament containing the same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2025-09-23 US disclosed
CN-114929779-B Method for producing aliphatic aromatic polyester 三菱化学株式会社 2025-05-02 CN disclosed
CN-116063257-B Anticancer drug intermediate and preparation method thereof 中国药科大学 2025-03-25 CN disclosed
EP-3851436-B1 NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME KAKEN PHARMA CO LTD (JP) 2024-06-12 EP disclosed
WO-2023149675-A1 POLYESTER RESIN COMPOSITION FOR FILM CONTAINING TITANIUM-BASED CATALYST AND PREPARATION METHOD THEREFOR 도레이첨단소재 주식회사 2023-08-10 WO disclosed
CN-116406231-A Molecules having certain pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2023-07-07 CN disclosed
US-20230086366-A1 Novel heteroaromatic amide derivative and medicament containing the same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2023-03-23 US disclosed
US-11472891-B2 Photocrosslinkable alginic acid derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US disclosed
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof JNC CORPORATION (JP) 2021-12-07 US disclosed
EP-0677524-A1 Thieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives as PAF antagonists Eisai Co., Ltd. (JP) 1995-10-18 EP disclosed
US-5438045-A An 3-acetyl-6-phenyl-2,3,4,5-tetrahydro-8h-pyrido(4'3':4,5)-thieno(3,2 -f)(1,2,4)triazolo(4,3-a)(1,4)diazepine derivative; antiallergens; asthma; antiplatelet activating factor activity EISAI CO., LTD. (JP) 1995-08-01 US disclosed
US-5409909-A Antiallergens EISAI CO., LTD. (JP) 1995-04-25 US disclosed
US-5382579-A Platelet activating factor antagonists; antiallergens; asthma EISAI CO., LTD. (JP) 1995-01-17 US disclosed
EP-0350958-B1 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI CHEMICAL IND (JP) 1994-12-21 EP disclosed
EP-0606103-A1 Thieno 3.2-f 1,2,4 triazolo 4,3-a 1,4 -diazepine derivatives as PAF antagonists Eisai Co., Ltd. (JP) 1994-07-13 EP disclosed
US-5304553-A Antiallergens; platelet activating factor inhibitor EISAI CO., LTD. (JP) 1994-04-19 US disclosed
US-5221671-A Antiallergens, bronchodilator agents EISAI CO., LTD. (JP) 1993-06-22 US disclosed
EP-0367110-A1 1,4-diazepine derivative and its pharmaceutical use Eisai Co., Ltd. (JP) 1990-05-09 EP disclosed
EP-0350958-A2 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230086366-A1 Novel heteroaromatic amide derivative and medicament containing the same SCN7A, HCN4, SCN4A GAA 3381/4885ALDH1A1 1627/4885LMNA 1156/4885
US-12421225-B2 Heteroaromatic amide derivative and medicament containing the same SCN7A, HCN4, SCN4A GAA 3549/4885ALDH1A1 1596/4885LMNA 877/4885
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof OCIAD2, PYM1, C1S GAA 4868/4885ALDH1A1 4091/4885LMNA 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.