SCHEMBL7520085

SCHEMBL7520085

CN(C)c1cc[c]c2c1-c1ccccc1C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 2/20 0.37
NSD2 O96028 1/20 0.37
EGFR P00533 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 1/20 0.33
PDK2 Q15119 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047396 0.78 MAOA (0.35) ALDH1A1MAPTLMNATDP1MEN1
SCHEMBL2045382 0.74 MAOA (0.32) ALDH1A1MAOABCHECES1
SCHEMBL7525313 0.74 MAPT (0.40) ALDH1A1L3MBTL1MAPTMAPK1TDP1
SCHEMBL5534770 0.74 MAPT (0.50) ALDH1A1L3MBTL1MAPTNSD2EGFR
SCHEMBL2050046 0.73 ADORA2A (0.37) ALDH1A1MAPK1MAOABCHECES1
Hydrochloric Acid SCHEMBL2864277 0.73 MAPT (0.49) ALDH1A1L3MBTL1MAPTNSD2EGFR
SCHEMBL5080844 0.72 PNMT (0.31) MAOARAB9A
SCHEMBL5086942 0.72 NR1H2 (0.36) ALDH1A1
SCHEMBL5087071 0.71 NR1H2 (0.38) ALDH1A1LMNA
SCHEMBL5086462 0.71 NR1H2 (0.38) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0773238-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2002-03-20 EP claimed
EP-0773239-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2001-12-05 EP claimed