SCHEMBL2047396

SCHEMBL2047396

Cc1cc[c]c2c1-c1ccccc1C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KMT2A Q03164 4/20 0.34
CASP3 P42574 2/20 0.34
CASP6 P55212 2/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
HTR2B P41595 1/20 0.32
MAP3K9 P80192 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2050323 0.80 GRIA1 (0.31)
SCHEMBL7525313 0.78 MAPT (0.40) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL7520085 0.78 ALDH1A1 (0.37) MAOAALDH1A1KDM4ELMNAMAPT
SCHEMBL2045382 0.78 MAOA (0.32) MAOAALDH1A1BCHECES1
SCHEMBL2050046 0.77 ADORA2A (0.37) MAOAALDH1A1HPGDBCHECES1
SCHEMBL5080844 0.76 PNMT (0.31) MAOANPC1RAB9APNMT
SCHEMBL8161482 0.74 MAOA (0.34) MAOAALDH1A1KDM4ENPC1LMNA
SCHEMBL6227101 0.74 HTR1A (0.36) KMT2ACASP3CASP6SENP8SENP7
SCHEMBL5086942 0.72 NR1H2 (0.36) ALDH1A1SLC6A2SLC6A4
SCHEMBL285403 0.72 APAF1 (0.34) MAOAALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779306-B1 Process for preparation of cycloolefin copolymers TICONA GMBH (DE) 2003-12-03 EP claimed
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed
CN-1067080-C Organometallic compound HOECHST AG (DE) 2001-06-13 CN claimed
US-5808122-A Organometallic compound HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
US-5726333-A POLYMERIZATION CATALYSTS HOECHST AG (DE) 1998-03-10 US claimed
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US claimed
CN-1068829-A Organometallic fluorenyl compounds and preparation thereof and application PHILLIPS PETROLEUM CO (US) 1993-02-10 CN claimed
CN-1066440-A Cyclopeutadiene type compounds and preparation method thereof PHILLIPS PETROLEUM CO (US) 1992-11-25 CN claimed
EP-3584075-B1 LAMINATE MITSUI CHEMICALS INC (JP) 2024-06-05 EP disclosed
US-11964447-B2 Laminate MITSUI CHEMICALS, INC. (JP) 2024-04-23 US disclosed
US-11905348-B2 Ethylene/alpha-olefin/non-conjugated polyene copolymer, method for producing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2024-02-20 US disclosed
EP-3584074-B1 LAMINATE MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
EP-3424705-B1 LAMINATE AND APPLICATION FOR SAME MITSUI CHEMICALS INC (JP) 2023-03-22 EP disclosed
CN-111868116-B Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof 三井化学株式会社 2022-12-09 CN disclosed
CN-1120545-A Organometallic compound HOECHST AG (DE) 1996-04-17 CN disclosed
EP-0704454-A2 Process for the preparation of a bridged metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed
EP-0694557-A2 Organo metallic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP disclosed
CN-1109472-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 1995-10-04 CN disclosed
CN-1107162-A Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 1995-08-23 CN disclosed
EP-0654476-A1 Metallocenes, their preparation and use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-24 EP disclosed