SCHEMBL7520129

SCHEMBL7520129

O=C(O)N1CCCCC1c1ccncc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 4/20 0.53
WDR77 Q9BQA1 4/20 0.53
SCD O00767 2/20 0.49
RIPK1 Q13546 1/20 0.47
HSD11B1 P28845 2/20 0.46
LMNA P02545 1/20 0.44
GPBAR1 Q8TDU6 1/20 0.43
ADAM17 P78536 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
SCD5 Q86SK9 2/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27574934 0.85 RIPK1 (0.62) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL216202 0.85 RIPK1 (0.62) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL27574946 0.85 RIPK1 (0.62) PRMT5WDR77SCDRIPK1HSD11B1
Water SCHEMBL27700791 0.83 RIPK1 (0.60) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL20449190 0.83 SCD (0.46) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL20528487 0.83 SCD (0.46) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL1197375 0.81 HSD11B1 (0.51) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL29892279 0.81 CCNC (0.51) RIPK1HSD11B1SCD5ALDH1A1KMT2A
SCHEMBL1197373 0.81 SCD (0.49) PRMT5WDR77SCDRIPK1HSD11B1
SCHEMBL14920930 0.81 HSD11B1 (0.54) RIPK1HSD11B1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN claimed
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN disclosed
US-20020173518-A1 Antithrombotic agents BEIGHT DOUGLAS WADE (US) 2002-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173518-A1 Antithrombotic agents SERPINC1, TFPI, F11 PRMT5 4201/4885WDR77 3565/4885SCD 3631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.