SCHEMBL752035

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755033	0.89	CSNK1A1 (0.33)	DAOPLA2G2A
	SCHEMBL755672	0.89	BACE1 (0.40)	BACE1LIPGDAOMAP2K7ESR1
	SCHEMBL752280	0.85	LIPG (0.45)	BACE1LIPGMAP2K7NAE1UBA3
	SCHEMBL752338	0.83	LIPG (0.39)	BACE1LIPGMAP2K7IDH1NAE1
	SCHEMBL753418	0.83	BACE1 (0.39)	BACE1LIPGDAOMAP2K7MAOB
	SCHEMBL752783	0.82	ACACB (0.38)	GRM5
	SCHEMBL755642	0.81	BACE1 (0.37)	BACE1LIPGDAOMAP2K7NAE1
	SCHEMBL756685	0.80	P2RX3 (0.38)	BACE1P2RX3LIPGDAOGRM5
	SCHEMBL755666	0.79	P2RX3 (0.35)	BACE1P2RX3LIPGDAOIDH1
	SCHEMBL752342	0.78	KMT2A (0.37)	BACE1POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.