SCHEMBL752338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752280	0.86	LIPG (0.45)	LIPGBACE1MAP2K7NAE1UBA3
	SCHEMBL752035	0.83	BACE1 (0.39)	LIPGBACE1MAP2K7NAE1UBA3
	SCHEMBL753418	0.83	BACE1 (0.39)	LIPGBACE1MAP2K7NAE1UBA3
	SCHEMBL755672	0.81	BACE1 (0.40)	LIPGBACE1MAP2K7NAE1UBA3
	SCHEMBL755642	0.81	BACE1 (0.37)	LIPGBACE1MAP2K7NAE1UBA3
	SCHEMBL752342	0.81	KMT2A (0.37)	BACE1POLBKMT2A
	SCHEMBL753054	0.75	LIPG (0.39)	LIPGBACE1
	SCHEMBL11389317	0.72	DHPS (0.49)	LIPGDHPSPARP1POLBCYP2D6
	SCHEMBL13754947	0.68	KCNH2 (0.56)	BACE1MAP2K7
	SCHEMBL11378618	0.66	TP53 (0.51)	LIPGDHPSPOLBCYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.