Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319172 | 0.89 | NPC1 (0.45) | MAPTMEN1CYP3A4PPARGKMT2A | |
| SCHEMBL19643784 | 0.87 | PKM (0.47) | MAPTMEN1KMT2AHPGDGAA | |
| SCHEMBL19659475 | 0.87 | PKM (0.47) | MAPTMEN1KMT2AHPGDGAA | |
| SCHEMBL16162246 | 0.85 | MEN1 (0.58) | MAPTMEN1CYP3A4PPARGKMT2A | |
| SCHEMBL13182705 | 0.81 | HPGD (0.62) | MAPTMEN1CYP3A4PPARGKMT2A | |
| SCHEMBL15067471 | 0.81 | HPGD (0.61) | MAPTMEN1KMT2ANPC1HPGD | |
| SCHEMBL7520394 | 0.80 | DRD3 (0.59) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7512700 | 0.79 | MAPT (0.64) | MAPTMEN1CYP3A4PPARGKMT2A | |
| SCHEMBL18998439 | 0.79 | TDP1 (0.56) | MAPTMEN1CYP3A4PPARGKMT2A | |
| SCHEMBL16171211 | 0.78 | ALDH1A1 (0.51) | MAPTMEN1CYP3A4PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | NANODESIGN INC. (CA) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | ESR2, ECE1, ECE2 | MAPT 4295/4885MEN1 1736/4885CYP3A4 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.