Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.59 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.59 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520362 | 0.80 | MAPT (0.50) | DRD2POLBMAPTALDH1A1MEN1 | |
| SCHEMBL15257179 | 0.79 | LTA4H (0.82) | DRD3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL14970684 | 0.79 | LTA4H (0.82) | DRD3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL16162246 | 0.79 | MEN1 (0.58) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7036874 | 0.78 | LTA4H (0.67) | DRD3DRD2PSMB1PSMB5PSMB2 | |
| Hydrochloric Acid SCHEMBL14966283 | 0.77 | LTA4H (0.79) | DRD3PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL29592170 | 0.77 | LTA4H (0.57) | DRD3DRD2PSMB1PSMB5PSMB2 | |
| SCHEMBL10688643 | 0.77 | LTA4H (0.66) | DRD3DRD2PSMB1PSMB5PSMB2 | |
| SCHEMBL2229668 | 0.77 | KDM4E (0.90) | DRD3DRD2PSMB1PSMB5PSMB2 | |
| SCHEMBL9056260 | 0.76 | PSMB1 (0.75) | PSMB1PSMB5PSMB2LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | NANODESIGN INC. (CA) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | ESR2, ECE1, ECE2 | DRD3 2682/4885DRD2 2893/4885PSMB1 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.