SCHEMBL7521178

SCHEMBL7521178

CCNc1ccc(CCNS(C)(=O)=O)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
ADRA2A P08913 2/20 0.40
ADRA2B P18089 2/20 0.40
ADRA2C P18825 2/20 0.40
ADRA1A P35348 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 2/20 0.40
RECQL P46063 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GRIA4 P48058 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12678530 0.78 ATM (0.57) MAPTADRA2AADRA2BADRA2CADRA1A
Sulfuric Acid SCHEMBL9564309 0.76 GAA (0.40) MAPTSMN1; SMN2ATMPOLBRECQL
SCHEMBL10635868 0.75 POLB (0.47) SMN1; SMN2POLBALDH1A1L3MBTL1
SCHEMBL8285545 0.74 TAAR1 (0.44) MAPTADRA2AADRA1AATMRECQL
SCHEMBL1924097 0.73 ESR1 (0.47) MAPTSMN1; SMN2POLBRECQLALDH1A1
SCHEMBL13503274 0.73 CYP3A4 (0.46) MAPTSMN1; SMN2POLBRECQLALDH1A1
Hydrochloric Acid SCHEMBL10904912 0.72 NQO2 (0.41) MAPTSMN1; SMN2ATMPOLBALDH1A1
SCHEMBL660035 0.72 ALDH1A1 (0.68) MAPTPOLBRECQLALDH1A1MEN1
SCHEMBL6535868 0.71 LMNA (0.38) MAPTSMN1; SMN2POLBRECQLALDH1A1
SCHEMBL15262269 0.71 L3MBTL1 (0.43) MAPTPOLBRECQLALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843213-B1 Photographic developer/amplifier process and solutions EASTMAN KODAK CO (US) 2002-03-13 EP disclosed
US-5968721-A REDOX DEVELOPER FOR PHOTOGRAPHIC IMAGES WITH DYE DEVELOPER, OXIDIZER AND HYDROXYLAMINE ANTIOXIDANT EASTMAN KODAK COMPANY (US) 1999-10-19 US disclosed
EP-0843213-A1 Photographic developer/amplifier process and solutions EASTMAN KODAK COMPANY (US) 1998-05-20 EP disclosed