Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521710 | 0.83 | TRPA1 (0.37) | TRPA1ATMALDH1A1HTR1BKDM4E | |
| SCHEMBL8387017 | 0.82 | ALDH1A1 (0.38) | ALOX5TRPA1ATMALDH1A1HTR1B | |
| SCHEMBL8377921 | 0.81 | TRPA1 (0.42) | TRPA1ATMALDH1A1HTR1BKDM4E | |
| SCHEMBL8444610 | 0.79 | GAA (0.43) | TRPA1ATMALDH1A1HTR1BGAA | |
| SCHEMBL7518276 | 0.77 | TRPA1 (0.37) | TRPA1ATMALDH1A1KDM4EGAA | |
| SCHEMBL7517858 | 0.75 | ALOX15 (0.43) | TRPA1ATMALDH1A1KDM4EGAA | |
| SCHEMBL7519263 | 0.74 | SCN2A (0.43) | TRPA1ATMALDH1A1GAAMEN1 | |
| SCHEMBL7517733 | 0.72 | TRPA1 (0.34) | TRPA1ATMALDH1A1GAAMAPT | |
| SCHEMBL7515890 | 0.69 | ALDH1A1 (0.41) | TRPA1ATMALDH1A1GAAMAPT | |
| SCHEMBL11316118 | 0.69 | TRPA1 (0.35) | TRPA1ATMALDH1A1HTR1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | claimed |