SCHEMBL7521673

SCHEMBL7521673

O=C(NCP(=O)(O)O)NCP(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 1/20 0.38
MMP2 P08253 5/20 0.37
KDM4E B2RXH2 1/20 0.37
THRB P10828 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP1 P03956 4/20 0.36
MMP3 P08254 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15610522 0.84 MMP2 (0.40) ENO1MMP2HSD17B10MMP1MMP3
SCHEMBL11137839 0.80 CRBN (0.33) ENO1
SCHEMBL3432246 0.79
SCHEMBL17190628 0.78 MMP2 (0.46) MMP2KDM4ETHRBMAPK1HSD17B10
SCHEMBL3888372 0.77
SCHEMBL3430053 0.77
SCHEMBL11494303 0.76 PPID (0.50) KDM4ETSHRMMP3
Urea SCHEMBL11142492 0.75 TDP1 (0.36) ENO1MMP2KDM4ETHRBMAPK1
Ethane SCHEMBL28815984 0.75 CYP2D6 (0.39) ENO1MMP2KDM4ETHRBMAPK1
SCHEMBL11021818 0.75 MEN1 (0.38) ENO1MMP2KDM4ETHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020058834-A1 Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter MONSANTO TECHNOLOGY LLC 2002-05-16 US claimed
WO-2001092208-A1 METAL-CATALYSED CARBOXYMETHYLATION IN THE PRESENCE OF A PROMOTER MONSANTO TECHNOLOGY LLC (US) 2001-12-06 WO claimed
US-10280189-B2 Method for the synthesis of aminoalkylenephosphonic acid MONSANTO TECHNOLOGY LLC (US) 2019-05-07 US disclosed
US-20150225431-A1 METHOD FOR THE SYNTHESIS OF AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC 2015-08-13 US disclosed
EP-2875036-A1 METHOD FOR THE SYNTHESIS OF AMINOALKYLENEPHOSPHONIC ACID Straitmark Holding AG (CH) 2015-05-27 EP disclosed
WO-2014012987-A1 METHOD FOR THE SYNTHESIS OF AMINOALKYLENEPHOSPHONIC ACID STRAITMARK HOLDING AG (CH) 2014-01-23 WO disclosed
US-20020058834-A1 Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter MONSANTO TECHNOLOGY LLC 2002-05-16 US disclosed
WO-2001092208-A1 METAL-CATALYSED CARBOXYMETHYLATION IN THE PRESENCE OF A PROMOTER MONSANTO TECHNOLOGY LLC (US) 2001-12-06 WO disclosed
US-4090959-A A PHOSPHONATE-SUBSTITUTED METHANESULFONAMIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-05-23 US disclosed
US-4055591-A METAL ION SEQUESTRANTS, FLAME RETARDANTS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-10-25 US disclosed
US-3992294-A UREAPHOSPHONATES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-16 US disclosed
US-3939226-A SEQUESTRANT, FIRE RETARDANT HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058834-A1 Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter BCAT2, GNMT, BCAT1 ENO1 725/4885MMP2 1251/4885KDM4E 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.