Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788898 | 0.91 | CA1 (0.37) | KDM4EALOX15CA1MAPTSMN1; SMN2 | |
| SCHEMBL2687920 | 0.85 | TDP1 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL6788905 | 0.83 | TDP1 (0.41) | TDP1EYA2APPACEKDM4E | |
| Water SCHEMBL7765711 | 0.83 | TDP1 (0.41) | TDP1EYA2APPACEKDM4E | |
| Water SCHEMBL7765705 | 0.83 | TDP1 (0.41) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7975927 | 0.78 | TDP1 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL4927059 | 0.76 | TDP1 (0.36) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL3714284 | 0.73 | LMNA (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7330656 | 0.71 | CYP2C19 (0.41) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7332844 | 0.71 | TDP1 (0.32) | TDP1EYA2APPACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058834-A1 | Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter | MONSANTO TECHNOLOGY LLC | 2002-05-16 | — | — | US | disclosed |
| WO-2001092208-A1 | METAL-CATALYSED CARBOXYMETHYLATION IN THE PRESENCE OF A PROMOTER | MONSANTO TECHNOLOGY LLC (US) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058834-A1 | Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter | BCAT2, GNMT, BCAT1 | TDP1 4724/4885EYA2 3445/4885APP 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.