Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919388 | 0.75 | MEN1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6919396 | 0.75 | MEN1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8008397 | 0.74 | MMP2 (0.52) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6048516 | 0.72 | KMT2A (0.58) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27448293 | 0.71 | CRHBP (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6808091 | 0.70 | MEN1 (0.52) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL6808095 | 0.70 | MEN1 (0.52) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL28532343 | 0.69 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL27448742 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL21800147 | 0.69 | CRHBP (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002542304-A | — | — | 2002-12-10 | — | — | JP | claimed |
| EP-1176985-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | Vectramed, Inc. (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000064486-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | VECTRAMED, INC. (US) | 2000-11-02 | — | — | WO | claimed |