Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448742 | 0.86 | ALDH1A1 (0.51) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7598909 | 0.83 | CRHBP (0.58) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6955073 | 0.82 | ALDH1A1 (0.79) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28532343 | 0.81 | ALDH1A1 (0.60) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6046672 | 0.80 | RAB9A (0.54) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21800147 | 0.78 | CRHBP (0.55) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20908975 | 0.77 | CRHBP (0.56) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3161760 | 0.76 | CRHBP (0.65) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16699713 | 0.76 | CRHBP (0.65) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27487794 | 0.76 | ALDH1A1 (0.50) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1115330-C | N- (4-amidinophenyl) glycinamide derivatives | HOFFMANN LA ROCHE (CH) | 2003-07-23 | — | — | CN | disclosed |
| CN-1224714-A | N- (4-amidinophenyl) glycinamide derivatives | HOFFMANN LA ROCHE (CH) | 1999-08-04 | — | — | CN | disclosed |