Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707411 | 0.88 | ALDH1A1 (0.41) | TP53MAPT | |
| SCHEMBL203341 | 0.88 | ALDH1A1 (0.41) | TP53MAPT | |
| SCHEMBL2706107 | 0.88 | ALDH1A1 (0.41) | TP53MAPT | |
| SCHEMBL28059729 | 0.86 | KLKB1 (0.33) | DGAT1KLKB1TP53MAPT | |
| SCHEMBL13132687 | 0.85 | AADAT (0.43) | DGAT1 | |
| SCHEMBL12332405 | 0.83 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL933739 | 0.81 | CCR1 (0.38) | DGAT1KLKB1CPT1ACPT2 | |
| SCHEMBL933198 | 0.81 | CCR1 (0.38) | DGAT1KLKB1CPT1ACPT2 | |
| SCHEMBL933196 | 0.79 | MAPT (0.32) | DGAT1CPT1ATP53MAPTCPT2 | |
| SCHEMBL933195 | 0.79 | MAPT (0.32) | DGAT1CPT1ATP53MAPTCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |