Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859593 | 0.84 | TSHR (0.58) | MAOBALOX5TSHRALDH1A1CYP2A6 | |
| SCHEMBL6429953 | 0.80 | LTA4H (0.69) | TDP1L3MBTL1LTA4HMAOBTSHR | |
| SCHEMBL28551906 | 0.80 | LTA4H (0.69) | TDP1L3MBTL1LTA4HMAOBTSHR | |
| SCHEMBL5580077 | 0.79 | LTA4H (0.57) | TRPA1LTA4HG6PC1TSHRALDH1A1 | |
| SCHEMBL5788290 | 0.79 | TDP1 (0.54) | TDP1L3MBTL1LTA4HMAOBALOX5 | |
| SCHEMBL16179089 | 0.77 | TRPA1 (0.55) | TDP1TRPA1LTA4HG6PC1MAOB | |
| SCHEMBL5632468 | 0.76 | GPR52 (0.54) | TDP1L3MBTL1TRPA1LTA4HG6PC1 | |
| SCHEMBL21835991 | 0.75 | IDO1 (0.52) | TRPA1ALOX5GSK3BTSHRALDH1A1 | |
| SCHEMBL21835990 | 0.75 | IDO1 (0.52) | TRPA1ALOX5GSK3BTSHRALDH1A1 | |
| SCHEMBL5795851 | 0.74 | IDO1 (0.61) | TDP1L3MBTL1LTA4HMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |