Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123173 | 0.92 | LTA4H (0.57) | LTA4HTRPA1G6PC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1930129 | 0.90 | ALDH1A1 (0.61) | LTA4HTRPA1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8710305 | 0.90 | TRPA1 (0.50) | LTA4HTRPA1G6PC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5632468 | 0.85 | GPR52 (0.54) | LTA4HTRPA1G6PC1ALDH1A1TP53 | |
| SCHEMBL4949651 | 0.84 | RELA (0.54) | ALDH1A1SMN1; SMN2TP53CYP2A6SIGMAR1 | |
| SCHEMBL3168388 | 0.83 | RELA (0.60) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 | |
| SCHEMBL7777160 | 0.83 | RELA (0.60) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 | |
| SCHEMBL8709613 | 0.82 | LTA4H (0.48) | LTA4HTSHR | |
| SCHEMBL7813380 | 0.82 | MAOB (0.63) | NPC1RAB9A | |
| SCHEMBL5253949 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | claimed |
| EP-2837635-B1 | NEW INTERMEDIATES FOR THE PREPARATION OF HEPARIN PENTASACCHARIDE AND PREPARATION METHODS THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2017-10-18 | — | — | EP | claimed |
| CN-111556872-B | Synthesis of borate derivatives and uses thereof | 梅琳塔治疗公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-2705028-B1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2019-08-21 | — | — | EP | disclosed |
| US-9725474-B2 | Modified nucleic acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| US-9556163-B2 | Process for the preparation of a rivaroxaban and intermediates formed in said process | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2017-01-31 | — | — | US | disclosed |
| CN-105579436-A | Onium salt, and composition containing same | ASAHI KASEI E MATERIALS CORP | 2016-05-11 | — | — | CN | disclosed |
| US-20160016983-A1 | New Modified Nucleic Acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-21 | — | — | US | disclosed |
| US-20140142303-A1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2014-05-22 | — | — | US | disclosed |
| EP-2705028-A1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | Egis Gyógyszergyár Nyilvánosan Müködö Részvény-Társaság (HU) | 2014-03-12 | — | — | EP | disclosed |
| US-20120302607-A1 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-11-29 | — | — | US | disclosed |
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| US-5023233-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0411833-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | disclosed |
| WO-1989000158-A1 | BRIDGED-DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS AND ESTERS | PFIZER INC. (US) | 1989-01-12 | — | — | WO | disclosed |
| EP-0297858-A2 | Bridged-diazabicycloalkyl quinolone carboxylic acids and esters | PFIZER INC. (US) | 1989-01-04 | — | — | EP | disclosed |
| EP-0005524-A1 | Omega-(1,3-dithiolan-2-imino)substituted acetic acids, process for their preparation and pharmaceutical compositions containing them | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1979-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016983-A1 | New Modified Nucleic Acid | RNGTT, RNASEH1, RNASE1 | LTA4H 3805/4885TRPA1 3635/4885G6PC1 476/4885 |
| US-20120302607-A1 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | ACACA, AKR1C4, HSD17B12 | LTA4H 118/4885TRPA1 4015/4885G6PC1 492/4885 |
| US-20140142303-A1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | CYP2C9, CYP3A5, CYP2J2 | LTA4H 2724/4885TRPA1 1977/4885G6PC1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.