Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520315 | 1.00 | HRH1 (0.62) | HRH1FNTAFNTBITGB3ITGA2B | |
| SCHEMBL7522265 | 0.89 | HRH1 (0.54) | HRH1ITGB3ITGA2BOPRK1CASP1 | |
| SCHEMBL9012056 | 0.86 | BCHE (0.49) | HRH1FNTAFNTBOPRK1PTAFR | |
| SCHEMBL5967157 | 0.78 | HRH1 (0.59) | HRH1ITGB3ITGA2BOPRK1TACR1 | |
| SCHEMBL15689075 | 0.77 | ITGB3 (0.63) | HRH1ITGB3ITGA2BOPRK1CASP1 | |
| SCHEMBL9012091 | 0.77 | BCHE (0.48) | HRH1OPRK1 | |
| SCHEMBL7519514 | 0.77 | HRH1 (1.00) | HRH1ITGB3ITGA2BOPRK1CASP1 | |
| SCHEMBL7525533 | 0.77 | HRH1 (1.00) | HRH1ITGB3ITGA2BOPRK1CASP1 | |
| SCHEMBL23856082 | 0.76 | HRH1 (0.57) | HRH1ITGB3ITGA2BOPRK1PPARG | |
| SCHEMBL23856080 | 0.76 | HRH1 (0.57) | HRH1ITGB3ITGA2BOPRK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739881-B1 | Piperidine derivatives | KOWA CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-0739881-A2 | Piperidine derivatives | KOWA CO. LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |