Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012056 | 0.92 | BCHE (0.49) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7522265 | 0.85 | HRH1 (0.54) | SETD7HRH1OPRK1 | |
| SCHEMBL7523574 | 0.77 | HRH1 (0.62) | HRH1OPRK1 | |
| SCHEMBL7520315 | 0.77 | HRH1 (0.62) | HRH1OPRK1 | |
| SCHEMBL10790294 | 0.75 | CTSL (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7536642 | 0.75 | CTSS (0.56) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL6661701 | 0.75 | CTSL (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4032986 | 0.75 | CTSS (0.56) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL24130351 | 0.74 | CTSK (0.56) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL8245664 | 0.74 | CTSK (0.56) | BCHEACHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739881-A2 | Piperidine derivatives | KOWA CO. LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |