Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519514 | 1.00 | HRH1 (1.00) | HRH1CASP1IDO1TDO2ITGB3 | |
| SCHEMBL19924794 | 0.77 | HRH1 (0.62) | HRH1CASP1IDO1TDO2ITGB3 | |
| SCHEMBL19924796 | 0.77 | HRH1 (0.62) | HRH1CASP1IDO1TDO2ITGB3 | |
| SCHEMBL7520315 | 0.77 | HRH1 (0.62) | HRH1CASP1ITGB3ITGA2BOPRK1 | |
| SCHEMBL7523574 | 0.77 | HRH1 (0.62) | HRH1CASP1ITGB3ITGA2BOPRK1 | |
| SCHEMBL5967157 | 0.75 | HRH1 (0.59) | HRH1ITGB3ITGA2BOPRK1 | |
| SCHEMBL15689075 | 0.74 | ITGB3 (0.63) | HRH1CASP1IDO1TDO2ITGB3 | |
| SCHEMBL23856082 | 0.73 | HRH1 (0.57) | HRH1IDO1TDO2ITGB3ITGA2B | |
| SCHEMBL23856080 | 0.73 | HRH1 (0.57) | HRH1IDO1TDO2ITGB3ITGA2B | |
| SCHEMBL29019148 | 0.70 | EPHX2 (0.55) | HRH1CASP1IDO1TDO2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739881-B1 | Piperidine derivatives | KOWA CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-0739881-A2 | Piperidine derivatives | KOWA CO. LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |