Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762751 | 0.80 | TOP2A (0.42) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL16597500 | 0.76 | TOP2A (0.50) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL378251 | 0.76 | TOP2A (0.50) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL10765254 | 0.72 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL27618934 | 0.72 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL11086765 | 0.72 | TOP2A (0.46) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL5592306 | 0.69 | TOP2A (0.48) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL631589 | 0.69 | TOP2A (0.48) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL3905229 | 0.69 | TOP2A (0.43) | TOP2ATOP2BALDH1A1MAPTTDP1 | |
| SCHEMBL6534567 | 0.69 | TOP2A (0.44) | TOP2ATOP2BALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816342-B1 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5883260-A | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0816342-A2 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |