SCHEMBL7523618

SCHEMBL7523618

Cc1ccc(C(OCCN(C)C)OCCN(C)C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.50
SLC6A2 P23975 5/20 0.50
SLC6A3 Q01959 5/20 0.50
CYP2D6 P10635 5/20 0.50
LMNA P02545 4/20 0.50
CHRM2 P08172 4/20 0.50
ADRA2A P08913 3/20 0.50
CHRM1 P11229 3/20 0.50
OPRM1 P35372 3/20 0.50
DRD3 P35462 3/20 0.50
ADRA2B P18089 3/20 0.50
HRH1 P35367 3/20 0.50
KCNH2 Q12809 3/20 0.50
CHRM4 P08173 2/20 0.50
CHRM5 P08912 2/20 0.50
CHRM3 P20309 2/20 0.50
HRH2 P25021 2/20 0.50
HTR2A P28223 2/20 0.50
HTR2C P28335 2/20 0.50
ADRA1A P35348 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(P-Tolyl)(Dimethylaminoethoxy)Methane SCHEMBL29519554 0.83 LMNA (0.71) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
SCHEMBL7524814 0.82 HTR2A (0.72) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
SCHEMBL9846188 0.79 CHRNA7 (0.43) SLC6A4SLC6A2SLC6A3LMNAKCNH2
SCHEMBL28837 0.79 SLC6A2 (0.83) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
Hydrochloric Acid SCHEMBL31097126 0.78 LMNA (0.84) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
Hydrochloric Acid SCHEMBL141104 0.76 SLC6A2 (0.75) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
SCHEMBL18806270 0.76 CHRNA7 (0.40) SLC6A4SLC6A2SLC6A3CYP2D6KCNH2
SCHEMBL9053497 0.74 MAPT (0.39) DRD3MAPK1SMN1; SMN2HRH3
Hydrochloric Acid SCHEMBL29519368 0.73 LMNA (0.84) SLC6A4SLC6A2SLC6A3CYP2D6LMNA
SCHEMBL3906858 0.73 ACHE (0.50) KDM4ENPSR1CHRNA7ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020056675-A1 Gas vent filter construction incorporating a hollow fiber membrane assembly MILLIPORE CORPORATION 2002-05-16 US disclosed
WO-2002018037-A2 GAS VENT FILTER CONSTRUCTION INCORPORATING A HOLLOW FIBER MEMBRANE ASSEMBLY MILLIPORE CORPORATION (US) 2002-03-07 WO disclosed
US-4369605-A Methods for preparing tube sheets for permeators having hollow fiber membranes MONSANTO COMPANY (US) 1983-01-25 US disclosed
US-4048107-A Polyurethane foam preparation using amio acetal catalyst OLIN CORPORATION (US) 1977-09-13 US disclosed