Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523679 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7519527 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7524518 | 0.76 | KDM4E (0.44) | MTNR1AKDM4EHPGDRAB9A | |
| SCHEMBL7519010 | 0.76 | HTR1A (0.38) | MTNR1A | |
| SCHEMBL9091731 | 0.76 | ALDH1A1 (0.43) | MTNR1AKDM4EALDH1A1 | |
| SCHEMBL7524073 | 0.76 | HTR1A (0.52) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL9093284 | 0.75 | GRIN2B (0.43) | MTNR1AKDM4EALDH1A1 | |
| SCHEMBL7521758 | 0.74 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| Bicarbonate SCHEMBL9415505 | 0.73 | CTNNB1 (0.44) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL9090101 | 0.71 | GRIN2B (0.44) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |