Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456728 | 0.87 | HTT (0.47) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL7460958 | 0.75 | GAA (0.40) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL7466102 | 0.73 | ALDH1A1 (0.50) | RAB9AALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8667765 | 0.71 | ALDH1A1 (0.56) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL7459262 | 0.71 | EPHX1 (0.54) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL7461854 | 0.71 | ALDH1A1 (0.41) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL7458253 | 0.69 | PDE4A (0.38) | RAB9ANPC1HTTALDH1A1THRB | |
| SCHEMBL8664999 | 0.67 | HTT (0.46) | RAB9ANPC1HTTALDH1A1MAPT | |
| SCHEMBL6949794 | 0.67 | HDAC1 (0.36) | THRBKMT2A | |
| SCHEMBL7456776 | 0.65 | PDE4A (0.37) | RAB9ANPC1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540193-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | claimed |