Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523894 | 0.80 | PTPN1 (0.48) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7523907 | 0.80 | PTPN1 (0.48) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7646101 | 0.78 | ALDH1A1 (0.42) | PTPN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7531126 | 0.76 | PTPN1 (0.63) | PTPN1HNF4APTPN6PTPN2RARA | |
| SCHEMBL7531117 | 0.76 | PTPN1 (0.63) | PTPN1HNF4APTPN6PTPN2RARA | |
| SCHEMBL7528656 | 0.75 | SNCA (0.47) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7528666 | 0.75 | SNCA (0.47) | PTPN1HNF4ASRD5A1SRD5A2KMT2A | |
| SCHEMBL7648629 | 0.74 | PTPN1 (0.38) | PTPN1KMT2AMEN1PTPN6PTPN2 | |
| SCHEMBL7646714 | 0.72 | PTPN1 (0.39) | PTPN1KMT2AMEN1HDAC6NPC1 | |
| SCHEMBL7646355 | 0.71 | ALDH1A1 (0.47) | PTPN1HNF4AKMT2AHDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |