Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521253 | 0.95 | TDP1 (0.42) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL7251881 | 0.87 | POLB (0.36) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL7529002 | 0.85 | TDP1 (0.41) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL7526587 | 0.79 | RAB9A (0.37) | NPC1RAB9AHPGDTSHRALDH1A1 | |
| SCHEMBL4577427 | 0.79 | TDP1 (0.73) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8038704 | 0.78 | HTT (0.76) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8038669 | 0.78 | HTT (0.76) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1404303 | 0.76 | TDP1 (0.68) | TDP1POLBAPEX1HTTRAB9A | |
| SCHEMBL9400724 | 0.76 | TSHR (0.64) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL632277 | 0.75 | NAAA (0.50) | HTTALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020039701-A1 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-04-04 | — | — | US | disclosed |