Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050696 | 0.87 | TP53 (0.33) | HRH3KEAP1NFE2L2HTTCYP1A2 | |
| SCHEMBL9705589 | 0.81 | TRPA1 (0.43) | HRH3KEAP1NFE2L2HTTCYP1A2 | |
| SCHEMBL9705573 | 0.79 | KCNA3 (0.50) | HRH3L3MBTL1 | |
| SCHEMBL4122924 | 0.78 | L3MBTL1 (0.53) | HTTCYP1A2CYP2C19LTA4HLMNA | |
| SCHEMBL4487824 | 0.78 | LTA4H (0.53) | CYP1A2LTA4HCYP2D6 | |
| SCHEMBL9705568 | 0.77 | KCNA3 (0.48) | — | |
| SCHEMBL10614694 | 0.77 | KCNA3 (0.48) | — | |
| SCHEMBL4086993 | 0.77 | TRPA1 (0.40) | HRH3KEAP1NFE2L2HTTCYP1A2 | |
| SCHEMBL9539656 | 0.77 | KCNA3 (0.48) | — | |
| SCHEMBL9829763 | 0.76 | ACACB (0.42) | HRH3KEAP1NFE2L2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690066-B1 | Phosphinic acid derivatives, their preparation as well as their use | AVENTIS PHARMA GMBH (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-5707979-A | INHIBITORS OF RETROVIRAL PROTEASE INHIBITORS FOR TREATMENT OF HIV | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0690066-A1 | Phosphinic acid derivatives, their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |