Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616262 | 0.86 | PLAU (0.38) | KDM2BCNR2ESR1MEN1KMT2A | |
| SCHEMBL8860947 | 0.81 | SLC6A3 (0.41) | ESR1 | |
| SCHEMBL22525083 | 0.80 | KDM2B (0.40) | KDM2BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7524110 | 0.78 | RECQL (0.43) | ALDH1A1PKMCNR2ESR1MEN1 | |
| SCHEMBL7598473 | 0.78 | KDM4E (0.46) | KDM2BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL734321 | 0.77 | FAAH (0.43) | KDM4EALDH1A1HPGDCNR2ESR1 | |
| SCHEMBL8058782 | 0.77 | FAAH (0.43) | KDM4EALDH1A1HPGDCNR2ESR1 | |
| SCHEMBL10199844 | 0.76 | PKM (0.39) | KDM4EPKMCNR2ESR1MEN1 | |
| SCHEMBL7598259 | 0.76 | MEN1 (0.51) | ALDH1A1CNR2EPHX2MEN1KMT2A | |
| SCHEMBL31236475 | 0.76 | MEN1 (0.51) | ALDH1A1CNR2EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0416038-A4 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | — | 1992-02-26 | — | — | EP | disclosed |
| EP-0416038-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. | TROPIX INC (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4952707-A | DECOMPOSITION TO LIGHT EMITTING FLUOROPHORE; ANALYSIS | TROPIX, INC. (US) | 1990-08-28 | — | — | US | disclosed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |