Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528940 | 0.96 | HTR1A (0.60) | HTR1AMTNR1ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7339688 | 0.80 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL8584312 | 0.75 | MTNR1A (0.60) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL28484062 | 0.74 | NPC1 (0.48) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL15064363 | 0.74 | HTR1A (0.96) | HTR1A | |
| SCHEMBL15064317 | 0.74 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6597071 | 0.74 | MTNR1A (0.59) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL6173819 | 0.74 | MTNR1A (0.59) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL13534264 | 0.74 | MTNR1A (0.64) | HTR1AMTNR1AMAPTSLC6A4 | |
| SCHEMBL3447188 | 0.73 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |