Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525811 | 0.96 | HTR1A (0.58) | HTR1AMTNR1ARAB9ANPC1HPGD | |
| SCHEMBL7339688 | 0.76 | RAB9A (0.60) | RAB9ANPC1HPGDTSHRMAPT | |
| SCHEMBL15064317 | 0.75 | HTR1A (1.00) | HTR1A | |
| SCHEMBL7531535 | 0.74 | MTNR1A (0.60) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL7522246 | 0.74 | MTNR1A (0.60) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL28415240 | 0.74 | NPC1 (0.47) | RAB9ANPC1HPGDTSHRALDH1A1 | |
| SCHEMBL11021052 | 0.74 | HPGD (0.66) | RAB9ANPC1HPGDTSHRMAPT | |
| SCHEMBL8584312 | 0.74 | MTNR1A (0.60) | HTR1AMTNR1ASLC6A4 | |
| SCHEMBL10525636 | 0.73 | RAB9A (0.60) | RAB9ANPC1HPGDTSHRMAPT | |
| SCHEMBL15064363 | 0.73 | HTR1A (0.96) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |