Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617501 | 1.00 | MEN1 (0.41) | MEN1KMT2APSEN1PSEN2SPPL2A | |
| SCHEMBL7615025 | 0.92 | MEN1 (0.41) | MEN1KMT2APSEN1PSEN2SPPL2A | |
| SCHEMBL7536470 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1TSHRPER2 | |
| SCHEMBL7613358 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1TSHRPER2 | |
| SCHEMBL7621987 | 0.84 | POLB (0.43) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL7527737 | 0.84 | POLB (0.43) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL7533145 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1PER2POLB | |
| SCHEMBL7530966 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1PER2POLB | |
| SCHEMBL5196623 | 0.82 | GRM2 (0.44) | MEN1KMT2AALDH1A1TSHRPOLB | |
| SCHEMBL7530130 | 0.82 | GRM2 (0.44) | MEN1KMT2AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |