SCHEMBL6554435

SCHEMBL6554435

Cc1cc(C(=O)NC(C)c2cc(C(=N)N)ccc2O)ccc1C(=O)N1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.42
PRSS1 P07477 4/20 0.42
ACACB O00763 1/20 0.40
F2 P00734 3/20 0.40
HSP90AA1 P07900 3/20 0.39
HSP90AB1 P08238 3/20 0.39
KLK1 P06870 1/20 0.37
KLK5 Q9Y337 1/20 0.37
PLAU P00749 2/20 0.36
PLAT P00750 2/20 0.36
PLG P00747 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7558537 0.99 F10 (0.41) F10PRSS1ACACBF2HSP90AA1
SCHEMBL6555783 0.90 MBTD1 (0.41) F10PRSS1F2HSP90AA1HSP90AB1
Hydrochloric Acid SCHEMBL7558653 0.89 MBTD1 (0.41) F10PRSS1F2HSP90AA1HSP90AB1
SCHEMBL7561837 0.89 F10 (0.50) F10PRSS1F2HSP90AA1HSP90AB1
Hydrochloric Acid SCHEMBL6555907 0.88 F10 (0.49) F10PRSS1F2HSP90AA1HSP90AB1
SCHEMBL7560667 0.86 F10 (0.41) F10PRSS1ACACBF2ITGB3
Hydrochloric Acid SCHEMBL7558907 0.85 F10 (0.41) F10PRSS1ACACBF2ITGB3
SCHEMBL6350317 0.84 ACACB (0.41) F10PRSS1ACACBF2PLAU
Hydrochloric Acid SCHEMBL6350375 0.83 ACACB (0.41) F10PRSS1ACACBF2PLAU
Hydrochloric Acid SCHEMBL6556783 0.82 ITGB3 (0.41) F10PRSS1ACACBF2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390357-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2004-02-25 EP claimed
WO-2002062778-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-08-15 WO claimed
EP-1390357-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co. KG (DE) 2004-02-25 EP disclosed
US-20020151534-A1 Antithrombotic compounds BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-10-17 US disclosed
WO-2002062778-A2 ANTI-THROMBOTIC COMPOUNDS, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151534-A1 Antithrombotic compounds SERPINC1, PF4, F2 F10 35/4885PRSS1 776/4885ACACB 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.