Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192897 | 0.83 | KIF11 (0.50) | KIF11 | |
| SCHEMBL7611296 | 0.83 | KIF11 (0.50) | KIF11 | |
| Cystine SCHEMBL27941982 | 0.79 | KIF11 (0.65) | KIF11GRIK1GRIK2 | |
| SCHEMBL11730116 | 0.75 | KIF11 (0.54) | KIF11ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL3668576 | 0.75 | KIF11 (0.59) | KIF11ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL503210 | 0.75 | KIF11 (0.59) | KIF11ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL16641857 | 0.74 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL16641859 | 0.74 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL31553575 | 0.73 | KMO (0.58) | KIF11ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1158095 | 0.72 | KIF11 (0.56) | KIF11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636183-B1 | COMPOSITIONS AND METHODS FOR PROTEIN STRUCTURAL DETERMINATIONS | MARTEK BIOSCIENCES CORP (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1193271-A2 | Compositions and methods for protein structural determinations | MARTEK BIOSCIENCES CORPORATION (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1191033-A2 | Compositions and methods for protein structural determinations | MARTEK BIOSCIENCES CORPORATION (US) | 2002-03-27 | — | — | EP | disclosed |
| US-5817474-A | GROWING MAMMAL OR INSECT CELL IN NUTRIENT MEDIUM, LABELING, ISOLATING LABELED PROTEIN, SUBJECTING TO NUCLEAR MAGNETIC RESONANCE SPECTROSCOPIC ANALYSIS | MARTEK BIOSCIENCES CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5627044-A | Compositions and methods for protein structural determinations | MARTEK BIOSCIENCES CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0636183-A4 | COMPOSITIONS AND METHODS FOR PROTEIN STRUCTURAL DETERMINATIONS. | MARTEK BIOSCIENCES CORP (US) | 1997-01-22 | — | — | EP | disclosed |
| EP-0636183-A1 | COMPOSITIONS AND METHODS FOR PROTEIN STRUCTURAL DETERMINATIONS | MARTEK BIOSCIENCES CORPORATION (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994018339-A1 | COMPOSITIONS AND METHODS FOR PROTEIN STRUCTURAL DETERMINATIONS | MARTEK BIOSCIENCES CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |