Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185010 | 0.85 | TSHR (0.49) | RAB9AMAPTMEN1KMT2AHTT | |
| SCHEMBL30727333 | 0.85 | TSHR (0.49) | RAB9AMAPTMEN1KMT2AHTT | |
| SCHEMBL13605636 | 0.84 | L3MBTL1 (0.53) | MEN1KMT2ACYP19A1ALDH1A1KDM4E | |
| SCHEMBL1185312 | 0.82 | TDP1 (0.57) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1542656 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4MAPTHTTCYP19A1 | |
| SCHEMBL5925504 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2682387 | 0.81 | MAPT (0.57) | CHRNB2CHRNA4RAB9AMAPTKMT2A | |
| SCHEMBL5642158 | 0.81 | RAB9A (0.45) | RAB9AMAPTMEN1KMT2AHTT | |
| SCHEMBL23754428 | 0.80 | PTGS2 (0.55) | MEN1KMT2AHTTALDH1A1TDP1 | |
| SCHEMBL7518552 | 0.79 | MAPT (0.46) | RAB9AMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |