Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.70 |
| ▸ | CA1 | P00915 | 10/20 | 0.70 |
| ▸ | CA9 | Q16790 | 11/20 | 0.59 |
| ▸ | CA12 | O43570 | 9/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398133 | 0.83 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| SCHEMBL27829 | 0.77 | SMN1; SMN2 (0.40) | CA2CA1 | |
| SCHEMBL1237755 | 0.77 | ALDH1A1 (0.57) | CA2CA1CA12CA14CA7 | |
| SCHEMBL8773769 | 0.77 | ALDH1A1 (0.52) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6541920 | 0.76 | CA2 (0.85) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3191992 | 0.76 | HTR6 (0.61) | LMNAMAPT | |
| SCHEMBL189005 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1803552 | 0.74 | CA2 (0.73) | CA2CA1CA9CA12CA14 | |
| SCHEMBL28032548 | 0.74 | CA2 (0.73) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1809238 | 0.74 | CA2 (0.73) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1414965-A | Sulfonamides and derivatives thereof that modulate the activeity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 2003-04-30 | — | — | CN | disclosed |
| EP-0691961-B1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | DU PONT PHARM CO (US) | 2002-02-13 | — | — | EP | disclosed |
| US-5712274-A | ANTIINFLAMMATORY, ANTIALLERGEN | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0691961-A1 | SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5212054-A | Multilayer, multicolor photographic film for high speed film | KONICA CORPORATION (JP) | 1993-05-18 | — | — | US | disclosed |
| US-4766120-A | ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0035046-B1 | NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |