Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR1F | P30939 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.51 |
| ▸ | TUBB | P07437 | 2/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671532 | 0.89 | HTR6 (0.68) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL7381366 | 0.83 | HTR6 (0.74) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL31744875 | 0.80 | HTR6 (0.62) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL6859385 | 0.79 | HTR6 (0.61) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL304796 | 0.77 | L3MBTL1 (0.55) | ALDH1A1MAPT | |
| SCHEMBL9094606 | 0.77 | HTR6 (0.73) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL3033159 | 0.76 | HTR6 (0.80) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL3029129 | 0.76 | HTR6 (0.75) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL13485649 | 0.76 | HTR6 (0.67) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL2204353 | 0.76 | HTR6 (0.74) | HTR6HTR1ADRD2DRD4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022576-A2 | 3-SUBSTITUTED INDOLE CARBOHYDRAZIDES USEFUL AS CELL PROLIFERATION AND ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-21 | — | — | WO | disclosed |