Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520579 | 0.84 | LMNA (0.44) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL6866913 | 0.75 | HTR2A (0.52) | PIM1HTR2AHTR2CHRH1SLC6A2 | |
| SCHEMBL7518024 | 0.75 | RET (0.47) | ALDH1A1PIM1L3MBTL1HTR2ALMNA | |
| SCHEMBL6865610 | 0.75 | PIM1 (0.45) | GAAMAPTALOX12TDP1POLB | |
| SCHEMBL5466833 | 0.74 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL2126069 | 0.74 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL19935227 | 0.73 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL21185020 | 0.73 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL10239427 | 0.73 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDALOX12 | |
| SCHEMBL6384769 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151553-A1 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | US | disclosed |
| US-6433165-B1 | ANTIINFLAMMATORY AGENTS | MILLENNIUM PHARMACEUTICALS, INC. | 2002-08-13 | — | — | US | disclosed |
| US-6323206-B1 | ANTIINFLAMMATORY AGENTS AND VIRICIDES FOR AIDS WITH CYTOKINESAND CHEMOKINES | MILLENNIUM PHARMACEUTICALS, INC. | 2001-11-27 | — | — | US | disclosed |
| US-4335122-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151553-A1 | Chemokine receptor antagonists and methods of use therefor | CCR1, CCR2, CCR5 | ALDH1A1 1711/4885GAA 4497/4885MAPT 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.