Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768347 | 0.76 | MAPT (0.42) | POLBNPY5RMEN1ALDH1A1LMNA | |
| SCHEMBL7610407 | 0.76 | GLA (0.48) | GLAPOLBNPY5RMEN1ALDH1A1 | |
| SCHEMBL7609912 | 0.75 | GLA (0.50) | GLAPOLBNPY5RMEN1ALDH1A1 | |
| SCHEMBL6538711 | 0.74 | ADRB3 (0.82) | ADRB3ADRB1 | |
| SCHEMBL7042491 | 0.69 | GAA (0.41) | ADRB3ADRB1MEN1ALDH1A1LMNA | |
| SCHEMBL10160174 | 0.68 | GAA (0.56) | ADRB3GLAALDH1A1LMNAGAA | |
| SCHEMBL9794603 | 0.67 | GLA (0.63) | GLAPOLBMEN1ALDH1A1LMNA | |
| SCHEMBL10345923 | 0.67 | LMNA (0.41) | ADRB3ADRB1POLBMEN1ALDH1A1 | |
| SCHEMBL5188506 | 0.65 | GLA (1.00) | GLAMAPK1MEN1ALDH1A1LMNA | |
| SCHEMBL6538997 | 0.65 | ADRB3 (0.82) | ADRB3ADRB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |