Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ibuprofen SCHEMBL11678091 | 0.83 | MAPT (0.70) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8244538 | 0.83 | SMN1; SMN2 (0.58) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20715473 | 0.82 | SMN1; SMN2 (0.54) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL10428743 | 0.82 | PTGS2 (0.65) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL19911172 | 0.81 | MAPT (0.65) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20067184 | 0.81 | SMN1; SMN2 (0.49) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8250876 | 0.80 | PTPN1 (0.71) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL9369312 | 0.80 | NPC1 (0.56) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL10160141 | 0.80 | SMN1; SMN2 (0.55) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL13024174 | 0.80 | SMN1; SMN2 (0.55) | GAAMAPTCRHBPCRHR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108934168-B | Improved methods for reprogramming non-pluripotent cells to pluripotent stem cells | 北昊干细胞与再生医学研究院有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-1146320-C | Enhancement of seed yield of soybeans by substituted benzoyl urea | 尤尼罗亚尔化学公司 | 2004-04-21 | — | — | CN | claimed |
| CN-1406110-A | Enhancement of seed/fruit/nut yield from flowering plants | UNIROYAL CHEM CO INC (US) | 2003-03-26 | — | — | CN | claimed |
| CN-1272040-A | Enhancement of seed yield of soybeans by substituted benzoyl urea | UNIROYAL CHEM CO INC (US) | 2000-11-01 | — | — | CN | claimed |
| CN-1221316-A | Benzoylurea insecticides on gene-modified Bt cotton | UNIROYAL CHEM CO INC (US) | 1999-06-30 | — | — | CN | claimed |
| EP-4691479-A2 | GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE | Janssen Biotech, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4194548-B1 | GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE | JANSSEN BIOTECH INC (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4602148-A1 | METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS | Peking University (CN) | 2025-08-20 | — | — | EP | disclosed |
| WO-2025069029-A1 | METHODS FOR REJUVENATING HUMAN CELLS | CENTARIX BIOTECH LTD (IL) | 2025-04-03 | — | — | WO | disclosed |
| US-11981929-B2 | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells | JANSSEN BIOTECH, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| WO-2024078119-A1 | METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS | PEKING UNIVERSITY (CN) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024078118-A1 | CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS | PEKING UNIVERSITY (CN) | 2024-04-18 | — | — | WO | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| CN-1217579-C | Benzoylurea insecticides on gene-modified Bt cotton | UNIROYAL CHEM CO INC (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1146320-C | Enhancement of seed yield of soybeans by substituted benzoyl urea | 尤尼罗亚尔化学公司 | 2004-04-21 | — | — | CN | disclosed |
| CN-1406110-A | Enhancement of seed/fruit/nut yield from flowering plants | UNIROYAL CHEM CO INC (US) | 2003-03-26 | — | — | CN | disclosed |
| CN-1272040-A | Enhancement of seed yield of soybeans by substituted benzoyl urea | UNIROYAL CHEM CO INC (US) | 2000-11-01 | — | — | CN | disclosed |
| CN-1221316-A | Benzoylurea insecticides on gene-modified Bt cotton | UNIROYAL CHEM CO INC (US) | 1999-06-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ADAMTS4, ADAMTS1, ADAMTS5 | GAA 504/4885MAPT 1366/4885CRHBP 784/4885 |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | GAA 352/4885MAPT 3533/4885CRHBP 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.