Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513585 | 0.78 | TRPV1 (0.43) | KIF11PTPRZ1PTPN1TRPV1TP53 | |
| SCHEMBL7789704 | 0.75 | MEN1 (0.32) | TDP1LMNA | |
| SCHEMBL998282 | 0.72 | ALDH1A1 (0.58) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 | |
| SCHEMBL4164368 | 0.72 | ALDH1A1 (0.52) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 | |
| SCHEMBL17870969 | 0.72 | ALDH1A1 (0.52) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 | |
| SCHEMBL423701 | 0.72 | EPHX2 (0.52) | KIF11TRPV1NPC1RAB9AEPHX2 | |
| SCHEMBL9842602 | 0.72 | ALDH1A1 (0.52) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 | |
| SCHEMBL222550 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7527160 | 0.72 | PTPRZ1 (0.50) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 | |
| SCHEMBL10965329 | 0.72 | KIF11 (0.67) | KIF11ALDH1A1KDM4ETDP1PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| CN-85101208-A | The preparation method of new N-(sulfo-) carbamyl aryl (sulfo-) formyl imidoether | — | 1987-01-24 | — | — | CN | disclosed |