Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842602 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL4164368 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL24265413 | 0.75 | TRPV1 (0.43) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL11123375 | 0.74 | KIF11 (0.63) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL5525900 | 0.74 | KIF11 (0.63) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL5531054 | 0.74 | KIF11 (0.90) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL656930 | 0.73 | ALDH1A1 (1.00) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL7527160 | 0.72 | PTPRZ1 (0.50) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL7527154 | 0.72 | KIF11 (0.49) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 | |
| SCHEMBL13981960 | 0.72 | TDP1 (0.47) | ALDH1A1TDP1KDM4EKIF11PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101626770-A | Use of TRPM5 Inhibitors for Modulating Insulin and GLP-1 Release | REDPOINT BIO CORP | 2010-01-13 | — | — | CN | claimed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| CN-104245689-B | Terazololine-one compound and its purposes as insecticide | 住友化学株式会社 | 2017-06-06 | — | — | CN | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |
| EP-2841429-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-20150051171-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-19 | — | — | US | disclosed |
| CN-104245689-A | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL CO | 2014-12-24 | — | — | CN | disclosed |
| WO-2013162072-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-31 | — | — | WO | disclosed |
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| CN-101626770-A | Use of TRPM5 Inhibitors for Modulating Insulin and GLP-1 Release | REDPOINT BIO CORP | 2010-01-13 | — | — | CN | disclosed |
| EP-1874871-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE Healthcare UK Limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |
| WO-2006111726-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL21, MRPL9 | ALDH1A1 2125/4885TDP1 3264/4885KDM4E 3025/4885 |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL9, MRPL21 | ALDH1A1 2134/4885TDP1 3231/4885KDM4E 3038/4885 |
| US-20150051171-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | CBR3, CYCS, CBR1 | ALDH1A1 1594/4885TDP1 4060/4885KDM4E 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.